Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:39 PM
Ignite Modification Date:
2025-12-24 @ 6:39 PM
NCT ID:
NCT03790657
Eligibility Criteria:
Inclusion Criteria:
* age 65 years or older
* preferred 10m walking speed \< 1.1 m/s
* self-report of "some difficulty with walking tasks, such as becoming tired when walking a quarter mile, or when climbing two flights of stairs, or when performing household chores."
* Willingness to be randomized to either study group and to participate in all aspects of study assessment and intervention
Exclusion Criteria:
* Diagnosed neurological disorder or injury of the central nervous system, or observation of symptoms consistent with such a condition (Alzheimer's, Parkinson's, stroke, etc.)
* Contraindications to non-invasive brain stimulation (e.g., metal in head, wound on scalp)
* Contraindications to magnetic resonance imaging (e.g., metal in body, claustrophobia, etc).
* Use of medications affecting the central nervous system
* severe arthritis, such as awaiting joint replacement
* severe obesity (body mass index \> 35)
* current cardiovascular, lung or renal disease; diabetes; terminal illness
* myocardial infarction or major heart surgery in the previous year
* cancer treatment in the past year, except for nonmelanoma skin cancers and cancers having an excellent prognosis (e.g., early stage breast or prostate cancer)
* current diagnosis of schizophrenia, other psychotic disorders, or bipolar disorder
* uncontrolled hypertension at rest (systolic \> 180 mmHg and/or diastolic \> 100 mmHg)
* bone fracture or joint replacement in the previous six months
* current participation in physical therapy for lower extremity function or cardiopulmonary rehabilitation
* current enrollment in any clinical trial
* difficulty communicating with study personnel, and/or non-English speaking
* planning to relocate out of the area during the study period
* clinical judgment of investigative team regarding safety or non-compliance
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
65 Years
Study:
NCT03790657
Study Brief:
Protocol Section:
NCT03790657