Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:38 PM
Ignite Modification Date:
2025-12-24 @ 6:38 PM
NCT ID:
NCT04340557
Eligibility Criteria:
Inclusion Criteria:
* Confirmed COVID-19 positive test result
* Mild to moderate respiratory symptoms of COVID-19.
* Systolic blood pressure ≥ 105 mmHg.
* Screen within 3 days of a positive COVID-19 test.
* Age ≥18 years old.
* Access to a phone in the hospital room or an electronic device that is capable of receiving phone or video calls.
* Able to read/write/speak English or Spanish fluently.
* Subjects must have the capacity to provide consent or an appropriate LAR to provide informed consent.
* Negative pregnancy test for women of childbearing potential and subject is randomized to the study arm.
Exclusion Criteria:
* Severe allergy to any ARB or ACE-inhibitor, including angioedema
* In the intensive care unit at screening.
* Home meds include any kind of ACE inhibitor or ARB
* Acute Kidney Injury (50% reduction in GFR from baseline at admission to any time during treatment in the study treatment arm)
* Hyperkalemia \>5.0 mmol/L at baseline or any time during treatment in the study treatment arm
* Creatinine Clearance \< 30 ml/min at baseline or any time during treatment in the study treatment arm
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04340557
Study Brief:
Protocol Section:
NCT04340557