Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:37 PM
Ignite Modification Date:
2025-12-24 @ 6:37 PM
NCT ID:
NCT03914157
Eligibility Criteria:
Inclusion Criteria
* Patients are between ages 40 and 80 years old.
* Patients with hypertension (Systolic BP\> 155 mm Hg) and/or requirement for two or more antihypertensive medications for more than 4 weeks, no restrictions on antihypertensive agents, although loop diuretics may be changed to diluting site agents (e.g. hydrochlorothiazide, indapamide, metolazone) for two weeks prior to study.
* Patients have serum creatinine ≤2.2 mg/dL.
* Patients have no contraindications to angiography: severe contrast allergy.
* Patients have no contraindications to no-contrast MR evaluations: e.g. pacemaker or magnetically active metal fragments, claustrophobia.
* Patients have the ability to comply with protocol
* Patients are competent and able to provide written informed consent
Exclusion Criteria
* Patient have serum creatinine \>2.2 mg/dL
* ARAS in a solitary kidney
* Patients have clinically significant medical conditions within the six months before SWT treatment: e.g. myocardial infarction, congestive heart failure, stroke, that would, in the opinion of the investigators, compromise the safety of the patient.
* Uncontrolled hypertension (Systolic BP \>180 mmHg despite therapy).
* Pacemaker, implantable defibrillator or other contraindication to MRI
* Inability to comply with breath-hold for 20 seconds
* Any active malignancy and undergoing therapy
* Patients are pregnant.
* Kidney or ureteric stone that may affect the effect of SWT.
* Another known acute or chronic kidney disease
* Local inflammation or infection over treatment areas.
* Bleeding disorders.
* Federal medical center inmates.
* Latex allergy
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Maximum Age:
80 Years
Study:
NCT03914157
Study Brief:
Protocol Section:
NCT03914157