Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:36 PM
Ignite Modification Date:
2025-12-24 @ 6:36 PM
NCT ID:
NCT07247357
Eligibility Criteria:
Inclusion Criteria:
* Are native Chinese. To qualify as a native Chinese for the purpose of this study, all 4 of the participant's biological grandparents must be of exclusive Chinese descent and born in China
* Are overtly healthy as determined by medical evaluation, including medical history, physical examination, vital signs, and electrocardiogram (ECG) at screening and admission
* Have clinical laboratory test results within the normal range for the population or investigative site, or with abnormalities deemed not clinically significant by the investigator at screening
* Have a body mass index within the range 18 to 32 kilogram per square meter (kg/m²)
Exclusion Criteria:
* History or presence of any of the following conditions, deemed clinically significant by the investigator (or designee), which may significantly alter the absorption, metabolism, or elimination of drugs, constitute a risk when taking the study intervention, or interfere with the data interpretation:
* metabolic disease, including congenital non-hemolytic hyperbilirubinemia, for example, Gilbert syndrome
* bile duct disease, including removal of the gall bladder
* digestive system disease
* blood disease
* disease of the nervous system
* significant history of, or presence of, liver disease, including any abnormal liver function tests, as defined by aspartate aminotransferase, alanine transaminase, or transducin beta-like above the 1.5× upper limit of normal range per the laboratory's reference ranges at screening, or
* clinically significant, active cardiovascular disease or history of heart attack within 6 months prior to the planned start of LY4064809
* Have a 12-lead ECG abnormality at screening or admission
* History of a major surgical procedure within 30 days prior to screening
* Diagnosed or treated cancer within 5 years prior to screening
* Have known allergies to LY4064809 or related compounds
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
21 Years
Maximum Age:
55 Years
Study:
NCT07247357
Study Brief:
Protocol Section:
NCT07247357