Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:33 PM
Ignite Modification Date:
2025-12-24 @ 6:33 PM
NCT ID:
NCT04963257
Eligibility Criteria:
Inclusion Criteria:
* The Diagnostic criteria of OCD in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-V), as well as the definition of refractory OCD, are as follows: failure to respond to oral treatment with at least two effective doses of antidepressants, including: Fluoxetine (≥20mg/ d), fluvoxamine (≥200mg/d), sertraline (≥150mg/d), and paroxetine (≥ 40mg/d) were all treated for at least 12 weeks. The Yale-Brown compulsive scale (Y-BOCS) score decreased by \< 35%.
* The total score of Yale- Brown compulsion scale (Y-BOCS) ≥16 points. (3)age 12 \~ 45 years.
Exclusion Criteria:
* Exclusion of severe organic brain disease;
* Severe physical illness;
* Other mental disorders such as tics, disruptive disorders, eating disorders and autism spectrum disorders;
* Pediatric streptococcal infection causedby autoimmune neuropsychiatric disease (PANDAS);
* Alcohol and drug dependence; Angle-closure glaucoma;
* Suicidal tendencies;
* Previous history of drug allergies related to research;
* Pregnant and lactating women.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
12 Years
Maximum Age:
45 Years
Study:
NCT04963257
Study Brief:
Protocol Section:
NCT04963257