Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:31 PM
Ignite Modification Date:
2025-12-24 @ 6:31 PM
NCT ID:
NCT00010257
Eligibility Criteria:
Inclusion Criteria:
* Histologically confirmed invasive, recurrent, or metastatic thymoma or thymic carcinoma not amenable to potentially curative therapy by surgery
* Extensive disease (distant disease, pleural disease, pulmonary with or without mediastinal disease, or recurrent progressive disease in site of prior radiotherapy)
* Advanced limited disease allowed if ineligible for primary radiotherapy or surgery
* Measurable disease
* Age 18 and over
* ECOG Performance Status 0-1
* Granulocyte count at least 1,500 cells/mm\^3
* Platelet count at least 100,000 cells/mm\^3
* Bilirubin no greater than 1.5 mg/dL
* Creatinine no greater than 2.0 mg/dL
* Concurrent corticosteroids for myasthenia gravis or other chronic conditions allowed
Exclusion Criteria:
* Acute concurrent complications such as infection or post-surgical complications
* Other prior malignancy within the past 5 years unless curatively treated with no evidence of recurrence
* Pregnant or nursing. A negative pregnancy test was required, and fertile patients must use effective contraception
* Prior chemotherapy for metastatic disease. Prior preoperative or adjuvant chemotherapy allowed if disease-free survival prior to recurrence was more than 1 year
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00010257
Study Brief:
Protocol Section:
NCT00010257