Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:29 PM
Ignite Modification Date:
2025-12-24 @ 6:29 PM
NCT ID:
NCT00082368
Eligibility Criteria:
* INCLUSION CRITERIA:
Patients must be eligible for enrollment in an active NCI (National Cancer Institute) protocol for treatment of cancer.
Patients greater than or equal to 18 years old.
Performance Status ECOG (Eastern Cooperative Oncology Group) 0 - 2.
Patients must be able to give informed consent.
Women of childbearing potential must have a negative pregnancy test within 24 hrs of Tc-94m injection.
Patients who have previously received tariquidar will be eligible, since no study has systematically shown loss of MDR-1 (Multi Drug Resistance Protein 1)/Pgp expression in tumors following exposure to both tariquidar and an anticancer agent.
An index lesion greater than 1.5 cm will be required to optimize the PET (positron emission imaging) images.
EXCLUSION CRITERIA:
Patients who are pregnant or breast-feeding will not be enrolled in order to prevent radiation exposure in the developing fetus or infant.
Patients weighing greater than 136 kg (the weight limit for the scanner table).
Patients having only tumor sizes less than 1.5 cm will be excluded.
HIV (human immunodeficiency virus) positive patients will be excluded to prevent potential drug interactions between tariquidar and antiretroviral agents.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT00082368
Study Brief:
Protocol Section:
NCT00082368