Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:27 PM
Ignite Modification Date:
2025-12-24 @ 6:27 PM
NCT ID:
NCT06887868
Eligibility Criteria:
Inclusion Criteria:
* male or female;
* aged over 45 years;
* clinically diagnosed with symptomatic unilateral KOA, classified as grade 1-3 according to the Kellgren and Lawrence system;
* fulfilled the classification criteria of the American College of Rheumatology for KOA;
* reported frequent episodes of pain in the knee joint during sit-to-stand movements for at least 3 months.
Exclusion Criteria:
* had KOA secondary to rheumatoid arthritis and other inflammatory and autoimmune conditions;
* reported lumbar pain radiating to the knee or lumbar pain as the primary complaint;
* had a history of knee or lower limb surgery;
* had a systemic or local infection;
* had received an intra-articular corticosteroid or hyaluronic acid injection within the past 6 months;
* reported current or past (within 4 weeks) oral corticosteroid use;
* had any condition in the lower limbs that would prevent performing the deep squat test;
* had clinical conditions in which manual therapy is generally contraindicated (such as fracture, osteoporosis, instability, infectious arthritis, tumors, joint ankylosis, acute inflammatory disorders, or lack of a diagnosed joint lesion).
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
45 Years
Study:
NCT06887868
Study Brief:
Protocol Section:
NCT06887868