Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 6:25 PM
Ignite Modification Date:
2025-12-24 @ 6:25 PM
NCT ID:
NCT06209268
Eligibility Criteria:
Inclusion Criteria:The participants of this study will be patients:
* admitted as sepsis in a medical ICU. The including criteria for sepsis will be defined according The Third International Consensus Definitions for Sepsis and Septic Shock. The sepsis will be defined as suspected infection with SOFA score\>=2.
* The subgroup of participants with septic shock will be defined as sepsis with vasopressor requirement to maintain a mean arterial pressure of 65 mm Hg or greater and serum lactate level greater than 2 mmol/L despite adequate fluid resuscitation.
Exclusion Criteria:
* total serum calcium ≥2.60 mmol/L,
* significant chronic end stage heart, kidney or liver disease
* active treatment with corticosteroids or cytotoxic drugs
* autoimmune diseases
* malignancies
* cachexia
* previously been on active vitamin D therapy the last four months prior to the study period.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
99 Years
Study:
NCT06209268
Study Brief:
Protocol Section:
NCT06209268