Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:58 PM
Ignite Modification Date:
2025-12-24 @ 5:58 PM
NCT ID:
NCT04980768
Eligibility Criteria:
Inclusion Criteria:
* Pulpal necrosis in mature mandibular molar as confirmed by negative response to pulp sensibility test (cold and electric pulp test)
* Radiographic evidence of apical periodontitis in the form of periapical radiolucency
* Radiographic alveolar bone breakdown not more than one third of root length.
Exclusion Criteria:
* Obese (BMI \>30 kg/m2), smoker, pregnant, diabetic, immunocompromised or have any other systemic inflammatory condition.
* Having a positive history of antibiotic use within the past month or require antibiotic premedication for dental treatment (including infective endocarditis or prosthetic joint prophylaxis).
* Teeth having previous root fillings, unrestorable teeth, fractured/perforated roots, grade 3 mobility, and history of recent periodontal therapy (within previous 6 months).
* Teeth with established endodontic-periodontal lesions exhibiting \<2 mm radiopaque bone between the root apex.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT04980768
Study Brief:
Protocol Section:
NCT04980768