Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:54 PM
Ignite Modification Date:
2025-12-24 @ 5:54 PM
NCT ID:
NCT06376968
Eligibility Criteria:
Inclusion Criteria:
* Male or female subjects ≥18 years of age
* Chronic bicarbonate standard high-flux haemodialysis or hemodiafiltration for at least 3 months
* Dialysis frequency 3 x per week
* Dialysis duration per session ≥ 4h
* Patient on chronic haemodialysis or hemodiafiltration prone to hypotensive episodes
* No residual renal function (definition: ≤100 ml urine/day) - changed to "No to minimal residual renal function (definition: ≤ 300 ml/day)" with Amendment 1 (CIP version 6)
* Stable dry body weight for at least 4 weeks
* Subjects who are willing to give a voluntary consent to participate in the study
Exclusion Criteria:
* Simultaneous participation in another interventional clinical trial (drugs or medical devices studies)
* Vascular access insufficiency (mean blood flow \<200ml/min)
* Patients treated with dialysis profiles: sodium profile, Ultrafiltration (UF) profile, and temperature profile - changed to: " Patients treated with dialysis profiles during the 9 prescreening visits: sodium profile, UF profile, and temperature profile. However, patients on sodium, ultrafiltration or temperature profiling expected to reduce intradialytic hypotensive episodes can be evaluated for enrollment when their frequency of sessions complicated by hypotension demonstrate the lack of efficacy of the applied profiles" with Amendment 1 (CIP version 6)
* Use of the BioLogic fusion function during the last 9 dialysis sessions recorded at the site (retrospective screening period)
* Pregnant or nursing women. Women of childbearing potential must agree to avoid pregnancy during the study period
* Factors which may interfere with full participation in the trial
* Any contra-indication to haemodialysis treatment per se, as described in the Instructions for Use (IFU)
* Any serious medical condition or disability, which in the opinion of the investigator limits the life expectancy and would preclude completion of the study
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06376968
Study Brief:
Protocol Section:
NCT06376968