Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:51 PM
Ignite Modification Date:
2025-12-24 @ 5:51 PM
NCT ID:
NCT02566668
Eligibility Criteria:
Inclusion Criteria:
* 18-65 years of age
* Non-smoker
* Asthmatic subjects must also demonstrate forced expiratory volume in 1 second (FEV1) bronchodilator reversibility ≥12% or airway hyperresponsiveness reflected by a methacholine provocative concentration causing a 20% fall in FEV1 (PC20) ≤16 mg/mL (Historical methacholine data from previous National Institutes of Health (NIH) trial will be allowed)
Exclusion Criteria:
* Greater than 10 pack year smoking history (none in the last year)
* Vocal cord dysfunction, cystic fibrosis or chronic obstructive pulmonary disorder
* Other lung disease, or any coronary artery disease, hypertension, diabetes or renal failure that is not well-controlled.
Healthy Controls only: Pre-bronchodilator FEV1/Forced vital capacity (FVC) \<0.70 or an improvement in FEV1 of more than 12% following 4 puffs of albuterol.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT02566668
Study Brief:
Protocol Section:
NCT02566668