Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:50 PM
Ignite Modification Date:
2025-12-24 @ 5:50 PM
NCT ID:
NCT00781768
Eligibility Criteria:
Inclusion Criteria:
* Diagnosis of cancer, admitted for myelosupppresive stem cell transplantation. Included preparative regimens include: TBI/VP16/CY, TBI/CY, BU/CY (PO \& IV), and BCV
* Age 18 or older
* Alcohol intake \<100 gm/d for the last year (\< approximately 5 drinks per day)
* Renal function: estimated or measured CrCl 50 ml/min
* Liver function: T.Bili \<1.5, AST \< 2x ULN, unless due to disease
* Able to swallow tablets and capsules
Exclusion Criteria:
* Age \< 18
* High alcohol intake \[\> 100 gm/d in the last year\]
* Allergy or intolerance to: ondansetron or dexamethasone
* Renal dysfunction \[measured or estimated CrCl \< 50 ml/min\]
* Liver dysfunction \[T.Bili \> 1.5, AST \> 2x ULN, unless due to disease\]
* Inability to swallow tablets or capsules
* Concurrent condition requiring systemic steroid use
* Nonmyeloablative SCT, patients receiving the conditioning regimens not included \[see inclusion criteria\]
* History of anticipatory nausea and vomiting
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00781768
Study Brief:
Protocol Section:
NCT00781768