Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:49 PM
Ignite Modification Date:
2025-12-24 @ 5:49 PM
NCT ID:
NCT03903068
Eligibility Criteria:
Inclusion Criteria:
1. A diagnosis of PSD is based on the "Depressive disorder due to another medical condition" of Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V);
2. Age 18-70 years old, gender is not limited;
3. Right-handed;
4. More than 6 months after the onset of stroke;
5. The duration of depressive disorder persists for more than two weeks;
6. Having the Hamilton Depression Rating Scale 17-Item (HAMD-17) scores higher than 17 at baseline;
7. Absence of psychiatric disorder or family history of psychosis before stroke;
8. Has never taken antidepressants before enrollment;
9. Having the level of audiovisual for examinations required for the study;
10. Providing signed informed consent.
Exclusion Criteria:
1. Patients with life expectancy \< 6 months;
2. Severe or unstable organic diseases;
3. Acute brain injury and infection;
4. The impaired skin integrity at the electrode placement site or skin allergic to electrode gel or adhesive;
5. Active current suicidal intent or plan as shown by a score of ≥ 3 on the suicide item of HAMD-17;
6. Current participation in any other clinical trial,;
7. Prior exposure to all kinds of neuromodulation treatments (including electroconvulsive therapy, TMS, tDCS, etc);
8. Prior exposure to any implanted device in body (including a cochlear implant, cardiac pacemaker, an implanted device or metal in the brain);
9. A history of brain organic diseases (including seizures, hydrocephalus, and brain tumors);
10. Any situations the investigators believe that they are not suitable for this study.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT03903068
Study Brief:
Protocol Section:
NCT03903068