Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:47 PM
Ignite Modification Date:
2025-12-24 @ 5:47 PM
NCT ID:
NCT05611268
Eligibility Criteria:
Inclusion Criteria:
1. Eisenmenger syndrome in functional class II, III or IV (World Health Organization for Pulmonary Hypertension).
2. Using or not oral anticoagulation with warfarin.
Exclusion Criteria:
1. Hospitalized.
2. History of relevant and/or repetitive bleeding.
3. Relevant comorbidities with specific treatments.
4. Systemic syndromes, except Down syndrome.
5. Candidates for surgical treatment of any nature, except dental.
6. Clinically manifest systemic infectious or inflammatory disease.
7. Thrombocytopenia (\<80x10\*9 platelets/L).
8. Patients in chronic anticoagulation regimen other than warfarin.
9. Diabetics individuals.
10. Pregnancy in progress, interruption of contraception or amenorrhea.
11. History of intolerance of pentoxifylline or other xanthine derivatives.
12. "Creatinine clearance" less than or equal to 30 mL/minute.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
10 Years
Maximum Age:
80 Years
Study:
NCT05611268
Study Brief:
Protocol Section:
NCT05611268