Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:39 PM
Ignite Modification Date:
2025-12-24 @ 12:39 PM
NCT ID:
NCT05827861
Eligibility Criteria:
Inclusion Criteria:
1. Aged 30-74 years;
2. Singapore citizen, or permanent resident
3. Able to read and understand English
4. Have access to and is comfortable using an internet-enabled device
5. At least 5% risk of CVD, as measured by the Framingham Risk Score (FRS), based on previous health screening results
Exclusion Criteria:
1. Existing heart disease or a prior history of coronary artery disease/angina/myocardial infarction/revascularisation, transient ischaemic attack/stroke, peripheral vascular disease, heart failure and cardiac arrhythmia
2. Suffering from cancer or chronic kidney disease
3. Currently prescribed with statins, exetimibe and pcsk-9 inhibitors to treat cholesterol levels
4. Been told by a doctor that they should only do physical activity recommended by a doctor due to a heart condition
5. Serious mental illness (Eg. A patient who is suffering from serious mental illness refers to those who need assistance in daily activities due to their mental illness.)
6. The following groups of individuals will be excluded as most of them would require pharmacological therapy for risk factors based on clinical guidelines in Singapore:
* Diagnosed with diabetes
* For those with FRS of 5-9%, LDL ≥160mg/dL
* For those with FRS of 10-19%, LDL ≥130mg/dL
* For those with FRS of ≥20%, LDL ≥100mg/dL
* Total cholesterol \>280 mg/dL at the point of screening
* Systolic blood pressure \>160 mmHg at the point of screening
* Triglycerides ≥4.5 mmol/L
7. Pregnant or planning to be pregnant in the next 7 months
8. Unable to give informed consent
9. Current or previous participants in HOPE Pilot Study, or HOPE-CVD-GP study
10. Members of the same household or family of existing enrolled participants
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
30 Years
Maximum Age:
74 Years
Study:
NCT05827861
Study Brief:
Protocol Section:
NCT05827861