Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:43 PM
Ignite Modification Date:
2025-12-24 @ 5:43 PM
NCT ID:
NCT02154568
Eligibility Criteria:
Inclusion Criteria:
* Healthy subjects:
* Normal PFT values: FEV1 \> 90% predicted; and Forced vital capacity (FVC) \> 90% predicted
* Normal chest x-ray (CXR)
* Medical history: No active pulmonary symptoms (cough, shortness of breath, sputum); Negative history of pulmonary disease; Negative smoking history (never smoked)
* Pulmonary Disease Subjects:
* PFT values: FEV1/FVC \< 70% (indicative of obstruction); and 30% \< FEV1 \< 50% predicted
* CXR normal except hyperinflation
* Symptoms - chronic shortness of breath
* All test subjects, healthy and with COPD should have similar physical anthropometric characteristics:
* Similar age with age difference less than 3 years
* Similar height (within 3-4 inches)
Exclusion Criteria:
* Any condition for which a MRI procedure is contraindicated.
* Presence of any non-MRI compatible metallic material in the body, such as pacemakers, metallic clips, etc.
* Likelihood of claustrophobia
* Chest circumference greater than that of the helium MR coil.
* Pregnancy, by report of subject. Clinically in the Department of radiology at UVA, self report is used when screening patients for MR scans as well as CT scans and fluoroscopy studies. If the subject reports there is any chance of their being pregnant a urine pregnancy test will be performed prior to any imaging.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT02154568
Study Brief:
Protocol Section:
NCT02154568