Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:40 PM
Ignite Modification Date:
2025-12-24 @ 5:40 PM
NCT ID:
NCT07068568
Eligibility Criteria:
Inclusion Criteria:
* Adults (≥18 years) with histologically confirmed, locally advanced periocular basal cell carcinoma (laBCC)
* Tumor location or extent deemed unsuitable for surgical resection or radiotherapy due to high risk of orbital invasion, vision loss, or cosmetic disfigurement
* ECOG performance status 0-2
* Life expectancy ≥12 months
* Willing and able to comply with study procedures and follow-up assessments
* Provided written informed consent
Exclusion Criteria:
* Evidence of metastatic basal cell carcinoma
* Prior treatment with Hedgehog pathway inhibitors
* History of other malignancies within 5 years (except adequately treated non-melanoma skin cancer or carcinoma in situ)
* Severe hepatic or renal impairment
* Active systemic infection or uncontrolled medical conditions
* Pregnant or breastfeeding women
* Inability to undergo dermatologic or ophthalmologic evaluation due to physical or cognitive impairment
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT07068568
Study Brief:
Protocol Section:
NCT07068568