Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:39 PM
Ignite Modification Date:
2025-12-24 @ 5:39 PM
NCT ID:
NCT05329168
Eligibility Criteria:
Inclusion Criteria:
* Age of 18 to 90 years
* Index blood culture collection within 96 hours prior to enrollment positive for S. aureus
* Experienced at least one sign or symptom related to SAB within past 96 hours prior to enrollment
* Known or suspected left- and/or right-sided endocarditis by modified Duke criteria and/or known or suspected complicated SAB
* Required duration of SOC antibiotic therapy ≤ 42 days
Exclusion Criteria:
* Previous receipt of LSVT-1701 or CF-301 (exebacase)
* Known hypersensitivity to kanamycin or other aminoglycosides
* Treatment with any potentially effective (anti-S. aureus) systemic antibiotic for \> 96 hours within 7 days before enrollment. Exception: Persistent S. aureus bacteremia after 96 hours of prior appropriate systemic antistaphylococcal antibiotic, and/or resistance to the prior systemic antibiotic
* Treatment with dalbavancin or oritavancin within the previous 90 days
* Known or suspected brain abscess or meningitis
* Community acquired pneumonia, nosocomial pneumonia because of pathogens other than S. aureus, or known polymicrobial bacteremia
* Presence of an intravascular infection source or extravascular material that cannot be removed within 96 hours after enrollment
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
90 Years
Study:
NCT05329168
Study Brief:
Protocol Section:
NCT05329168