Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:39 PM
Ignite Modification Date:
2025-12-24 @ 5:39 PM
NCT ID:
NCT04395768
Eligibility Criteria:
Inclusion Criteria:
1. Age ≥ 18 years
2. Provision of informed consent in writing, can be electronic
3. Diagnosis of active COVID-19
Exclusion Criteria:
1. Known G6PD deficiency
2. Contra-indication to hydroxychloroquine, azithromycin or Vitamin C: allergy to study interventions, epilepsy, serious hearing or visual problems, history of severe depression, calcium oxalate stones, advanced liver disease, pregnancy or lactating
3. Already receiving chloroquine, azithromycin, \>3 grams Vitamin C daily or an experimental antiviral
4. History of fever (e.g. night sweats, chills) and/or acute respiratory infection (e.g. cough, shortness of breath, sore throat) of more than 7 days' duration. Note, if study numbers not quickly reached, the investigators may decide to include those with symptoms of longer than 7 days
5. Calculated creatinine clearance of \< 30 mL/minute
6. Baseline ECG showing: QTc ≥470 for males, QTc ≥480 for females
7. Receipt of a drug known to increase QTc: quetiapine, amiodarone, sotalol
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT04395768
Study Brief:
Protocol Section:
NCT04395768