Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:39 PM
Ignite Modification Date:
2025-12-24 @ 5:39 PM
NCT ID:
NCT00438568
Eligibility Criteria:
Inclusion Criteria:
* Age 55 or greater
* Good physical health
* Memory impairment with a diagnosis of mild cognitive impairment (MCI) or Alzheimer's disease (AD)
* Participants on stable doses of Memantine (Namenda) or cholinesterase inhibitors will be eligible
Exclusion Criteria:
* Chronic sinus problems/allergies with chronic use of nasal decongestants or antihistamines
* Significant neurologic disease that might affect cognition (other than AD), such as stroke, Parkinson's disease, multiple sclerosis, severe head injury with loss of consciousness for more than 30 minutes or with permanent neurologic symptoms
* Significant medical illness or organ failure, such as uncontrolled hypertension or cardiovascular disease, chronic obstructive pulmonary disease, liver disease, or kidney disease
* Preexisting diabetes or current or previous use of hypoglycemic agents or insulin; participants will be excluded if they have a fasting blood sugar greater than 165 on baseline OGTT
* Clinically significant elevations in liver function tests, cholesterol, or triglycerides
* Major psychiatric disorders (e.g., untreated major depression and schizophrenia)
* Chronic use of the following types of medications: anti-psychotic, anxiolytic, and opiates
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
55 Years
Study:
NCT00438568
Study Brief:
Protocol Section:
NCT00438568