Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:37 PM
Ignite Modification Date:
2025-12-24 @ 5:37 PM
NCT ID:
NCT01521468
Eligibility Criteria:
Inclusion Criteria:
* First presentation to cardiologist with suspected coronary artery disease
* No documented prior history of coronary artery disease
* Intermediate pre-test likelihood for coronary artery disease as defined by Diamond and Forrester criteria
* Clinically referred for invasive coronary angiography
* Age above 40 years
Exclusion Criteria:
* History of severe chronic obstructive pulmonary disease (COPD) or chronic asthma
* Pregnancy
* Renal failure ( i.e. estimated glomerular filtration rate \< 45 mL/min)
* Use of sildenafil (Viagra) or dipyridamole (Persantin) that can not be terminated.
* Contra-indications for β-blockers
* Allergic reaction to iodized contrast
* Concurrent or prior (within last 30 days) participation in other research studies using investigational drugs
* Claustrophobia
* Significant co-morbidities
* Atrial fibrillation, second or third degree atrioventricular block
* Tachycardia
* Acute myocardial infarction
* Heart failure
* Left ventricle ejection fraction estimated \< 50%
* Cardiomyopathies
* Previous radiation exposure in the diagnostic work-up
* Subjects intended for short-term medical treatment or an invasive coronary intervention
* No informed consent
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Study:
NCT01521468
Study Brief:
Protocol Section:
NCT01521468