Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:30 PM
Ignite Modification Date:
2025-12-24 @ 5:30 PM
NCT ID:
NCT04819568
Eligibility Criteria:
Inclusion Criteria:
\- Cirrhotics including ACLF with septic shock requiring norepinephrine dose \>0.5ug/kg/min to maintain MAP\> 65 mm Hg
\- An informed consent from the patient or relative
Exclusion Criteria:
* Patients with age less than 18 years or more than 65 years
* Severe known cardiopulmonary disease (Hypertension, structural or valvular heart disease, coronary artery disease, arrhythmias)
* Stroke
* Peripheral Vascular disease
* Gut Paralysis
* Intestinal obstruction
* Cancer, hepato-cellular carcinoma (HCC), intrahepatic or extrahepatic malignancy
* Portal vein thrombosis
* Hepatic vein outflow tract obstruction (HVOTO )
* Pregnancy
* Patients with Pa02/FiO2 ratio \<150
* Severe coagulopathy platelets \<20,000 and INR \> 4
* Active Bleed (Mucosal or variceal)
* Patients already on terlipressin in the last 48 hours
* Extremely moribund patients with an expected life expectancy of less than 24 hours
* Failure to give informed consent from family members.
* Patient enrolled in other clinical trials
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT04819568
Study Brief:
Protocol Section:
NCT04819568