Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:25 PM
Ignite Modification Date:
2025-12-24 @ 5:25 PM
NCT ID:
NCT05375968
Eligibility Criteria:
Inclusion Criteria:
* Between 18 and 50years of age
* Cases: Diagnosis of POTS with presyncope symptoms after meals Or
Controls:
* With no significant past medical history, non-smokers and not on chronic medications.
* Body mass index (BMI) between 18.5 to 29.9 kg/m2
* If pre-menopausal women: must have regular menstrual cycle.
Exclusion Criteria:
* BMI above ≥30 kg/m2
* Irregular menstrual cycle
* Intolerance to CPAP.
* Chronic use of acetaminophen
* Heart problems: myocardial infarction, angina, heart failure, stroke
* Undergone any heart related procedures or stents or on pacemaker.
* Uncontrolled hypertension.
* Type 1 or type 2 diabetes mellitus
* Pregnant or breast-feeding women.
* Impaired liver function
* Impaired Kidney function test.
* Anemia (Hematocrit\<34%).
* Ongoing substance abuse.
* Subjects with abnormal EKG
* History of seizures.
* Diagnosed with neuropathy due to any reason
* History of neck surgery.
* Smoker,
* On statin therapy for high cholesterol
* Rheumatoid arthritis.
* On oral corticosteroids,
* Current infections
* Documented of moderate decrease in blood volume
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
50 Years
Study:
NCT05375968
Study Brief:
Protocol Section:
NCT05375968