Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:25 PM
Ignite Modification Date:
2025-12-24 @ 5:25 PM
NCT ID:
NCT03037450
Eligibility Criteria:
Inclusion Criteria:
* Patient older than 18.
* NK stages 2 and 3 (Mackie's classification).
* Non-response to maximal medical treatment (lachrymal substitution, autologous serum).
* Postherpetic or post-zoster NK (Group 1).
* Postoperative NK (neurosurgery and trigeminal thermocoagulation) (Group 2).
* Posttraumatic NK (orbital trauma, ocular burn) (Group 3).
* No ocular hypertony in both eyes.
* Visual acuity \> 20/40 on the contralateral eye.
* Written consent of the patient.
* Patient benefiting from national health coverage (either as a direct user or beneficiary).
Exclusion Criteria:
* Impossibility of general anesthesia.
* Herpetic or zoster recurrence in the 6 months prior surgery.
* Length of NK evolution \> 5 years.
* Congenital NK.
* Bilateral NK.
* Other causes of NK: diabeta mellitus, amylosis, sarcoidosis, multiple sclerosis, vitamin A or B12 deficiency, Sjögren syndrome, GVH disease, topical NSAID, topical beta-blockers, history of refractive surgery.
* Mental illness.
* Adult with legal guardian or guardianship.
* Pregnancy.
* Breast-feeding.
* Patient's unable to understand informations.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03037450
Study Brief:
Protocol Section:
NCT03037450