Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:24 PM
Ignite Modification Date:
2025-12-24 @ 5:24 PM
NCT ID:
NCT03436550
Eligibility Criteria:
Inclusion Criteria:
* Chronic liver disease (including all etiologies of liver disease)
* 18 years of age and older
* Patient is able to give informed consent for this study
* Patients preferably (but not necessarily) underwent/will undergo:
1. Liver biopsy (percutaneous or transjugular or surgical) performed within 6 months, as part of routine clinical care and/or HVPG measurement as part of their clinical care (within 6 months) and/or clinically indicated upper gastrointestinal endoscopy.
and/or
2. Liver transplant or liver resection performed as part of routine clinical care and/or
3. Medical therapy for portal hypertension or TIPS placement as part of routine clinical care.
Control group
* Healthy volunteers without history of liver disease (will be used for the purpose of image optimization). These subjects will NOT undergo HVPG measurement.
* 18 years of age and older
Exclusion Criteria:
* Age less than 18 years
* Unable or unwilling to give informed consent
* Contra-indications to MRI
1. Electrical implants such as cardiac pacemakers or perfusion pumps
2. Ferromagnetic implants such as aneurysm clips, surgical clips, prostheses artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants
3. Ferromagnetic objects such as jewelry or metal clips in clothing
4. Pregnant subjects
5. Pre-existing medical conditions including a likelihood of developing seizures or claustrophobic reactions.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03436550
Study Brief:
Protocol Section:
NCT03436550