Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:21 PM
Ignite Modification Date:
2025-12-24 @ 5:21 PM
NCT ID:
NCT06371950
Eligibility Criteria:
Inclusion Criteria:
* Signed informed consent obtained prior to any study-related activities
* Postmenopausal female patients of London Health Sciences Centre (LHSC) aged 55-75 years
* Scheduled to undergo primary total knee replacement for osteoarthritis
Exclusion Criteria:
* Unable to understand and respond to the provided questionnaires
* Male sex
* Inflammatory arthritis
* Periprosthetic infection
* Prior surgery with hardware insertion in the target knee
* Metabolic syndrome
* Inflammatory bowel disease
* Body mass index \<18.5 kg/m2
* Immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment)
* Any contraindications for PET-MRI
* Allergy to cephalosporin antibiotics
Healthy Volunteers:
False
Sex:
FEMALE
Minimum Age:
55 Years
Maximum Age:
75 Years
Study:
NCT06371950
Study Brief:
Protocol Section:
NCT06371950