Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:21 PM
Ignite Modification Date:
2025-12-24 @ 5:21 PM
NCT ID:
NCT01985750
Eligibility Criteria:
Inclusion Criteria:
* Males and females with chronic lung disease, aged between 45 and 85 years old who have been referred for pulmonary rehabilitation.
* The subject is able and willing to give fully informed consent.
Exclusion Criteria:
Any of the commonly accepted contraindications to MRI scanning, for example, severe claustrophobia, presence of metallic implants, a pacemaker etc.
* Pregnancy. The risk to foetus of radiofrequency energy of the MRI scan is unknown.
* Inadequate understanding of verbal and written information in English, sufficient to complete an MRI safety screening.
* Unable to lie flat and still for 1/2 hour
* Requirements for oxygen therapy
* Significant cardiac, neurological, psychiatric or metabolic disease
* Contra-indications to d-cycloserine: Alcoholism, known hypersensitivity, severe renal failure
* Regular therapy with prescribed opioid analgesics
* Antidepressant therapy (this may alter hippocampal plasticity)
* Previous pulmonary rehabilitation (because the learning may be different on repeat pulmonary rehabilitation treatments)
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
45 Years
Maximum Age:
85 Years
Study:
NCT01985750
Study Brief:
Protocol Section:
NCT01985750