Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:18 PM
Ignite Modification Date:
2025-12-24 @ 5:18 PM
NCT ID:
NCT00228150
Eligibility Criteria:
Inclusion Criteria:
* Male or female outpatients.
* Age \>=35 years at screening.·
* Diagnosis of Parkinson's syndrome, on at least two of the three key Parkinson's symptoms, i.e. resting tremor, bradykinesia and rigidity.
* Duration of the disease of less than 3 years since diagnosis·
* Modified Hoehn and Yahr stage \<= 2.5.
* Untreated patients.
* Generally healthy and ambulatory.
* Patient has given his informed written consent and is capable of following study procedures.
Exclusion Criteria:
* Any indication of forms of parkinsonism other than PD.
* Severe resting tremor.
* Presence of either dyskinesia, fluctuations, or loss of postural reflexes·
* Treatment with L-Dopa, dopamine agonist, amantadine, anticholinergics, catechol-o-methyltransferase (COMT ) inhibitors, selegiline, dopamine receptor antagonists, catecholamine depleters, indirect dopamine agonists or alphamethyldopa.
* Electroconvulsive therapy (ECT).
* Use of CYP3A4 strong, and moderate inducers or inhibitors.
* Participation in another clinical trial with an investigational drug within two months prior to randomization.
* Dementia, uncontrolled depression, psychotic disorder.
* History of substance-related disorders including alcohol or other substance use disorders.
* Females of child bearing potential.
* Evidence (detected by history, physical examination and/or laboratory/ECG tests) of any clinically significant or unstable medical disorder that could interfere with the patient's participation in the clinical trial; interfere with the absorption, metabolism or excretion of the study medication; or interfere with the evaluation of the study drug.
* Alterations of laboratory tests or ECG findings of potential clinical significance.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
35 Years
Study:
NCT00228150
Study Brief:
Protocol Section:
NCT00228150