Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:12 PM
Ignite Modification Date:
2025-12-24 @ 5:12 PM
NCT ID:
NCT04197050
Eligibility Criteria:
Inclusion Criteria:
* Age between 18-75 years old.
* confirmed CTD（including systemic lupus erythematosus, myositis, polymyositis, systemic sclerosis, sarcoid, Sjögren's syndrome or mixed connective tissue disease）
* SLEDAI ≤ 6 in patients with SLE or ESR ≤ 30 in patients with SSc
* already have OPT for CTD at least 3 month
* RVEF ≤ 45%
* Providing written informed consent
Exclusion Criteria:
* Documented coronary artery disease or prior angiography for coronary artery disease (\>50% stenosis).
* Patients with known congenital heart disease or other systemic diseases that might induce RVrEF.
* Patients with standard metallic contraindications to CMR or an estimated glomerular filtration rate \< 30 ml/min/1.73 m2.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
75 Years
Study:
NCT04197050
Study Brief:
Protocol Section:
NCT04197050