Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:12 PM
Ignite Modification Date:
2025-12-24 @ 5:12 PM
NCT ID:
NCT02864550
Eligibility Criteria:
The inclusion criteria for this study are as follows:
1. Males, ≥ 18 years of age at baseline;
2. Self-reported MSM status;
3. Self-report condomless anal sex with a man within the last 6 months;
4. Laboratory documentation of HIV-1 infection;
5. Prior diagnosis of early/infectious syphilis (i.e. primary, secondary or early latent) within preceding 36 months (defined on the basis of a new positive serum rapid plasma reagin (RPR) test, or ≥2-dilution rise in titre if previous syphilis, or positive darkfield microscopy result or T. pallidum direct fluorescent antibody test or PCR from a primary lesion);
6. Able to provide informed consent.
The exclusion criteria for this study are as follows:
1. Known allergy or intolerance to doxycycline or tetracyclines;
2. A known diagnosis of myasthenia gravis;
3. Use of medications which could lower doxycycline levels, including barbiturates, phenytoin and carbamazepine;
4. Individuals using isotretinoin;
5. Any individual capable of getting pregnant.
Healthy Volunteers:
False
Sex:
MALE
Minimum Age:
18 Years
Study:
NCT02864550
Study Brief:
Protocol Section:
NCT02864550