Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 5:04 PM
Ignite Modification Date:
2025-12-24 @ 5:04 PM
NCT ID:
NCT00498550
Eligibility Criteria:
Inclusion Criteria:
* Meets Diagnostic and Statical Manual of Mental Disorders IV (DSM-IV) diagnostic criteria for schizophrenia or schizoaffective disorder
* Meets diagnostic criteria for marijuana use disorder, as determined by a rating of 3 or higher on the Drug Use Scale (Abuse or Dependence)
* Used marijuana on 5 or more days during the 3 weeks prior to study entry
* Taking any oral antipsychotic other than clozapine in the month prior to study entry. (Patients may take a second oral antipsychotic medication, if approved by the Medication Adjustment Group)
* If female, willing to use effective contraception throughout the study
Exclusion Criteria:
* Unable to take clozapine for medical reasons, including previous clozapine-induced granulocytopenia, myeloproliferative disorder, white blood cell count less than 3500/mm3, or history of seizures
* Currently taking clozapine
* Currently taking other psychotropic medications for the treatment of substance use (e.g., disulfiram, naltrexone, acamprosate, inderol, tegretol, topiramate, and pramipexole)
* Participated in a clinical trial of an investigational drug within 30 days of study entry
* Currently participating in a psychosocial intervention clinical trial
* Has medical or legal problems that may entail a jail or hospital stay during the study
* Has a developmental disability that would make study participation difficult
* Currently enrolled in a live-in treatment program for substance use disorders
* Pregnant or plans to become pregnant during the study
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT00498550
Study Brief:
Protocol Section:
NCT00498550