Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:54 PM
Ignite Modification Date:
2025-12-24 @ 4:54 PM
NCT ID:
NCT03982550
Eligibility Criteria:
Inclusion Criteria:
* Community-dwelling and living independently (without need of assistance).
* Interest and availability for participation in a 12-week planned RT program at the CERC, including pre- and post- testing.
* Competency in English sufficient for assessment and training.
* Able to see and hear sufficiently to participate in RT.
* Not engaged in any structured exercise training outside of this intervention.
* Eligible to undergo MRI.
* Answer NO to all questions on the Physical Activity Readiness Questionnaire (PAR-Q) or receive medical clearance from a physician.
Exclusion Criteria:
* Possible Dementia (score less than or equal to 23 on MMSE).
* History of known neurological disease (e.g. Epilepsy, Multiple sclerosis, Parkinson disease, Alzheimer's disease), cerebral infarct (e.g. Stroke), or traumatic brain injury.
* History of known cardiovascular or metabolic disease or chronic illness which may compromise the patient's ability to safely perform the RT program (e.g. coronary artery disease, arrhythmia, asthma requiring an inhaler during exercise), or presently uncontrolled hypertension (SBP \> 140 mmHg or DBP \> 90 mmHg). Patient may be required to provide clearance from a physician at the study team's discretion.
* Type 1 or Type 2 Diabetes.
* Changes in chronic pharmacological treatment (e.g. Aspirin, Statins, or ACE inhibitors) or hormone therapy during the intervention period.
* Current treatment for congestive heart failure, angina, uncontrolled arrhythmia, DVT or other cardiovascular event.
* Myocardial infarction, coronary artery bypass grafting, angioplasty or other cardiac condition in the past year.
* Contraindications against MRI (e.g. metal implants, claustrophobia).
* Self-report regular heavy RT in the past 6 months (i.e. "strengthening exercises or lifting weights heavy enough that you could not perform more than 15 repetitions in one set").
* Musculoskeletal injuries interfering with the ability to perform RT or medical conditions for which exercise in contraindicated.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
60 Years
Maximum Age:
80 Years
Study:
NCT03982550
Study Brief:
Protocol Section:
NCT03982550