Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:54 PM
Ignite Modification Date:
2025-12-24 @ 4:54 PM
NCT ID:
NCT00700050
Eligibility Criteria:
Inclusion Criteria:
FEMALES WITH CF
* Sexually mature female CF patients followed at the Toronto CF Clinics of The Hospital for Sick Children (adolescents) or St. Michael's Hospital (adults)
* 14-28 years of age
* Diagnosis of CF is based on a typical clinical picture and confirmed by repeated sweat chloride values \> 60 mEq/L as determined by pilocarpine ionophoresis (minimum 100mg sweat)
* Have regular, normal menses
* Able to give consent on her own behalf
FEMALES WITHOUT CF
* Sexually mature females
* 14-28 years of age
* Have regular, normal menses
* Able to give consent on her own behalf
MALES WITH CF
* Sexually mature male CF patients followed at the Toronto CF Clinics of The Hospital for Sick Children (adolescents) or St. Michael's Hospital (adults)
* 14-28 years of age
* Diagnosis of CF is based on a typical clinical picture and confirmed by repeated sweat chloride values \> 60 mEq/L as determined by pilocarpine ionophoresis (minimum 100mg sweat)
* Able to give consent on his own behalf
MALES WITHOUT CF
* Sexually mature males
* 14-28 years of age
* Able to give consent on his own behalf
Exclusion Criteria:
* Is a smoker
* Has had an upper respiratory tract infection within the preceding two weeks
* Is taking systemic oral contraceptive therapy
* Is pregnant
* Has used furosemide or amiloride or had a pulmonary exacerbation in the previous month (Acute exacerbations are defined as 3 or more of the following symptoms or signs: increased cough, change in volume, colour or thickness of the sputum, fever, hemoptysis, increased shortness of breath, change in their chest radiograph or a fall in pulmonary function (FEV1) of \>10% from baseline)
* Unable to give consent on his/her own behalf
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
14 Years
Maximum Age:
28 Years
Study:
NCT00700050
Study Brief:
Protocol Section:
NCT00700050