Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:52 PM
Ignite Modification Date:
2025-12-24 @ 4:52 PM
NCT ID:
NCT01522950
Eligibility Criteria:
Inclusion Criteria:
* borderline blood pressure (120-145/80-90 mm Hg);
* borderline or abnormal small artery elasticity (C2) as measured by pulse contour analysis;
* treatment-naive for all blood pressure medications including diuretics for at least 30 days prior to baseline visit;
* able to walk on a treadmill for 3 minutes;
* female patients with reproductive potential must use an approved contraceptive method if appropriate (for example, intrauterine device \[IUD\], birth control pills, or barrier device during and for 1 month after the last dose of study drug;
* voluntary written informed consent before performance of any study-related procedure not part of normal medical care, with the understanding that consent may be withdrawn by the subject at any time without prejudice to future medical care.
Exclusion Criteria:
* history of intolerance to beta-blockers or clear contraindications to their use; current pharmaceutical treatment of blood pressure;
* known history of cardiovascular disease (myocardial infarction, coronary artery bypass graft, unstable angina, uncontrolled arrhythmias, stroke, etc.);
* known history of diabetes; known history of hepatic, renal or gastrointestinal disorder;
* known history of any illness that may cause additional risk (as determined by study investigator);
* pregnant or lactating women \[when used during pregnancy, beta-blockers may cause fetal harm\];
* participation in a concomitant clinical trial.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
80 Years
Study:
NCT01522950
Study Brief:
Protocol Section:
NCT01522950