Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:45 PM
Ignite Modification Date:
2025-12-24 @ 4:45 PM
NCT ID:
NCT04303650
Eligibility Criteria:
Inclusion Criteria:
* Anticipated to be mechanically ventilated to \>48hour and expected to Stay in ICU \> 4 days.
* No contraindication to early enteral nutrition.
* Enteral feeding in the first 24 hours after admission, with a minimum protein contribution of 1 gm / kg / day.
* We recruited only well nourished, previously healthy patients with no past history of nutritional problems.
Exclusion Criteria:
* Patients with preexisting neuromuscular pathology, lower limb amputation, skeletal fractures or immobilization in the previous 2years.
* Patients with relevant Co-morbidities (renal, liver or heart disease or COPD), previous immune abnormalities including those receiving corticosteroids, and those with past or recent history of cancer.
* Patients with anuria owing to the difficulty in evaluating excreted urea nitrogen
* Whose ultrasound data will be missing or incomplete
* Pregnancy
* Patients who will not reach the goal in enteral protein intake for any reason (gastrointestinal intolerance, contraindication to enteral feeding or repeated interruptions of enteral feeding due to multiple surgical procedures) or those who start parenteral nutrition.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT04303650
Study Brief:
Protocol Section:
NCT04303650