Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:22 PM
Ignite Modification Date:
2025-12-24 @ 12:22 PM
NCT ID:
NCT00315861
Eligibility Criteria:
Inclusion Criteria:
* Histologically proven advanced solid tumors
* Measurable or evaluable disease
* Age ≥ 18 years
* Karnofsky performance status ≥ 80% (ECOG 0 or 1)
* Adequate liver, bone marrow and kidney function
Exclusion Criteria:
* More than 3 prior chemotherapy regimens in the metastatic setting
* Prior treatment with topotecan or pemetrexed
* Clinically significant third space fluid present at the time of treatment
* Unable to interrupt aspirin, other non-steroidal anti-inflammatory drugs
* Inability to take steroid premedications or vitamin supplementation
* The presence of active brain metastases
* Prior radiotherapy within 4 weeks prior to the first day of treatment
* Prior surgery within 3 weeks prior to the first day of treatment
* Prior chemotherapy within 3 weeks prior to the first day of treatment
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT00315861
Study Brief:
Protocol Section:
NCT00315861