Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:22 PM
Ignite Modification Date:
2025-12-24 @ 12:22 PM
NCT ID:
NCT07187661
Eligibility Criteria:
Inclusion Criteria:
* Confirmed diagnosis of Hemophilia A.
* Presence of one or more target joints (knee, elbow, ankle) with chronic synovitis and a history of \>2 hemarthrosis episodes in the past 6 months.
* Target joint World Federation of Hemophilia (WFH) joint score of 2-3.
* Adequate hematological, renal, and liver function (as specified by protocol lab values).
* Ability and willingness to provide informed consent and comply with the study protocol.
Exclusion Criteria:
* HIV positive diagnosis.
* Severely damaged joints or anatomical limitations preventing safe injection.
* Contraindications to MRI.
* Uncontrolled hypertension.
* Recent major surgery/trauma (\<28 days).
* Serious non-healing wound, active cardiovascular disease, or other significant comorbidities that could increase risk or interfere with the study.
Healthy Volunteers:
False
Sex:
ALL
Study:
NCT07187661
Study Brief:
Protocol Section:
NCT07187661