Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:36 PM
Ignite Modification Date:
2025-12-24 @ 4:36 PM
NCT ID:
NCT03140566
Eligibility Criteria:
Inclusion Criteria:
* Hospitalization for ADHF with dyspnea ≥NYHA III, peripheral edema, and pulmonary congestion (rales on auscultation or pulmonary vascular congestion on chest radiograph)
* Age ≥18 years
* NT-proBNP \>300 ng/l within 24 h after admission
* Sufficient ultrasound visualization to evaluate IVC
* IVCmax \>2.1 cm and IVCCI ≤50 % in the baseline assessment within 24 h after admission
* Capability to sign informed consent personally
Exclusion Criteria:
* Cardiogenic shock with systolic blood pressure \<90 mmHg plus end-organ hypoperfusion
* ADHF due to significant arrhythmias
* Severe pulmonary disease as primary cause of dyspnea
* Simplified Modification of Diet in Renal Disease estimated glomerular filtration rate \<30 ml/min/1.73 m²
* Need for non-invasive or invasive ventilation support at baseline
* Pregnancy
* Participation in another interventional trial regarding heart failure treatment
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03140566
Study Brief:
Protocol Section:
NCT03140566