Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:36 PM
Ignite Modification Date:
2025-12-24 @ 4:36 PM
NCT ID:
NCT03646266
Eligibility Criteria:
Inclusion Criteria:
* high respiratory drive, defined as tidal volume \> 8ml/kg PBW on inspiratory support of 12 cmH2O.
* sedation level: richmond agitation-sedation scale (RASS) ≤ -3
* ventilated in pressure support mode
Exclusion Criteria:
* recent use of NMBA (\< 2 hrs)
* arterial pH \< 7.25
* hemodynamic instability, i.e. high dose vasopressors (\>0.5 μg/kg/min) or inotropes (dobutamine \>15 μg/kg/min or enoximone \>25 μg/kg/min)
* intracranial pressure \> 20 cmH2O
* past medical history of neuromuscular disorders
* known pregnancy
* known previous anaphylactic reaction to NMBA's.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT03646266
Study Brief:
Protocol Section:
NCT03646266