Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:31 PM
Ignite Modification Date:
2025-12-24 @ 4:31 PM
NCT ID:
NCT01823666
Eligibility Criteria:
Inclusion Criteria:
* complaint about cognitive decline compared to previous performance
* objective cognitive impairment in one or more cognitive domains for age
* preservation of independence in functional abilities
* Mini-Mental State Examination(MMSE) scores between 24 and 30
* a Clinical Dementia Rating(CDR) score of 0.5
Exclusion Criteria:
* dementia
* patient with any following disease: Parkinson's disease, multiple system atrophy, normal pressure hydrocephalus, progressive supranuclear palsy, subarachnoid hemorrhage, brain neoplasms, Huntington disease, epilepsy
* depression(HAMD \>7) or psychosis
* uncontrolled severe medical conditions(i.e., acute heart failure, renal insufficiency)
* current treatment with benzodiazepines, antidepressants, antipsychotics, or other medications with significant psychotropic or central cholinergic effects
* abnormal thyroid, low vitamin B12 level or low folic acid level
* patient with visual and auditory disorders can't cooperate with neuropsychological assessment
* patient can't cooperate with following up
* informed consent is not obtained
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
40 Years
Maximum Age:
85 Years
Study:
NCT01823666
Study Brief:
Protocol Section:
NCT01823666