Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:26 PM
Ignite Modification Date:
2025-12-24 @ 4:26 PM
NCT ID:
NCT04941066
Eligibility Criteria:
Inclusion Criteria:
* Good general health
* DSM-5 diagnosis of major depressive disorder (MDD)
Exclusion Criteria:
General Exclusion Criteria:
* Pregnancy
Medical Conditions:
* Moderate to severe traumatic brain injury (\>30 min. loss of consciousness or \>24 hours posttraumatic amnesia) or other neurocognitive disorder with evidence of neurological deficits.
* Presence of co-morbid medical conditions not limited to but including cardiovascular (e.g., history of acute coronary event, stroke) and neurological diseases (e.g., Parkinson's disease), as well as pain disorders.
* Presence of an uncontrolled medical condition that is deemed by the investigators to interfere with the proposed study procedures, or to put the study participant at undue risk.
Psychiatric Disorders:
* Current severe suicidal ideation or attempt within the past 12 months.
* Psychosis
* Bipolar disorder
* Substance abuse or dependence within the previous 6 months
Contraindications for MRI:
* Bodily implants of unsafe paramagnetic materials such as pace-makers and aneurysm clips.
* Claustrophobia that is severe enough to preclude MRI scanning.
Medications:
* Evidence of recreational drug use from a urine test.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
65 Years
Study:
NCT04941066
Study Brief:
Protocol Section:
NCT04941066