Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:22 PM
Ignite Modification Date:
2025-12-24 @ 4:22 PM
NCT ID:
NCT02129166
Eligibility Criteria:
Inclusion Criteria:
* under healthy condition
* Non-smokers (self-reported) age 18 -55 years
* Body Mass Index (BMI) between 18 to 30 kg/m2 inclusive
* Signed Informed Consent
Exclusion Criteria:
* Any evidence of renal dysfunction (estimated creatinine clearance \< 80ml/min).
* Any evidence of impaired hepatic function (liver enzymes greater than two times the upper limit of normal or total bilirubin \> 2.0 mg/dL).
* Taking any medications other than oral contraceptives or hormonal replacement therapy.
* Use of any known inhibitor or inducer of CYP3A or P-gp within 30 days prior to study drug administration.
* Consumption of alcohol, grapefruit, star fruit, grapefruit products or star fruit products within the 72-hour period prior to study drug administration.
* Women who are pregnant or currently breastfeeding.
* Donation or loss of 550 mL or more blood volume (including plasmapheresis) or receipt of a transfusion of any blood product within 8 weeks prior to initial study drug administration.
* Known adverse effect or intolerance to imatinib or dasatinib.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
55 Years
Study:
NCT02129166
Study Brief:
Protocol Section:
NCT02129166