Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:20 PM
Ignite Modification Date:
2025-12-24 @ 4:20 PM
NCT ID:
NCT02432066
Eligibility Criteria:
Inclusion Criteria:
* Minimum of 12 years of education
* Must report typical daily smoking of \> 10 cigarettes/day over the previous year
* Must report a history of at least 3 years of regular smoking
* Must provide carbon monoxide measures of at least 6.5 ppm
* Must report a willingness to quit smoking
Exclusion Criteria:
* Participants engaged in behavioral and/or nicotine replacement therapies, or assisted quit efforts, within previous 6 months.
* Must not meet criteria for other substance dependence or major psychiatric disorders.
* Must be absent chronic medical conditions that might jeopardize health and safety, confound data interpretation or that contraindicate the administration of compounds acting at nAChR sites. This list includes disorders with direct effects on neurologic function (e.g., seizure disorders, transient ischemic events, chronic or active hepatic disease), metabolic disorders (e.g., uncontrolled Type 2 diabetes), or cardiovascular disease (e.g., hypertension, mitral valve compromise, tachycardia, or irregular heart rates).
* Must not smoke only cigars, pipes or hookahs or use nicotine products but not cigarettes
* Must not report current use of nicotine replacement therapies (i.e., occasions of \> 4 h/week during a typical week, even if not used as a cessation aid)
* Must not have used bupropion within the previous year
* Must not report any past use (regardless of year) of varenicline
* Women may not be breastfeeding, pregnant or intending to become pregnant during the study period
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
25 Years
Maximum Age:
60 Years
Study:
NCT02432066
Study Brief:
Protocol Section:
NCT02432066