Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:18 PM
Ignite Modification Date:
2025-12-24 @ 4:18 PM
NCT ID:
NCT05916066
Eligibility Criteria:
Inclusion criteria for glaucoma patients:
* Manifest glaucoma (PEXG, HTG, NTG) in one or two eyes,
* age \> 18 years,
* replicable visual field defects that cannot be explained by any other disease or insult,
* suspect/anomalous optic nerve head or abnormalities in the retinal nerve fiber layer.
Inclusion criteria for age-matched controls:
-A normal visual field and optic nerve, age \> 18 years.
Exclusion criteria for all:
* Any disease affecting retinal function (such as more than mild macular degeneration or diabetic retinopathy), neurological or other non-glaucomatous conditions that may affect the visual field,
* inability to perform a perimetric exam,
* resistance in quitting intake of multivitamins or B-vitamins,
* allergy to NAM or niacin, previous eye surgery involving the central retina,
* pregnant or breast-feeding women,
* fertile women not using reliable contraception,
* diagnosis of cancer in the last five years (not including treated squamous cell carcinoma), anamnesis of liver-disease or peptic ulcer,
* not able to speak and understand either Swedish or English.
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05916066
Study Brief:
Protocol Section:
NCT05916066