Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 12:19 PM
Ignite Modification Date:
2025-12-24 @ 12:19 PM
NCT ID:
NCT00902161
Eligibility Criteria:
Inclusion Criteria:
* Participant has Type 2 Diabetes (T2DM)
* Participant is either: Not on an oral antihyperglycemic medication for at least 6 weeks; on a single oral antihyperglycemic medication that is not a peroxisome proliferator-activated gamma (PPAR-gamma) agonist (e.g. Avandia); OR on a combination of no more than two antihyperglycemic medications that are not PPAR-gamma) agonists
* Participant has not received insulin for at least 6 months
* Participant has not been treated with a PPAR-gamma agonist for at least 12 weeks
* Participant has been a nonsmoker for at least 6 months
* Female participants who are non-pregnant and highly unlikely to conceive due to surgical sterilization, post-menopausal status, not heterosexually active, or willing to use 2 birth control methods
Exclusion Criteria:
* Participant has a history of stroke, seizures, or neurological disorders
* Participant cannot tolerate insulin or propranolol
* Participant has a history of asthma, emphysema or chronic bronchitis
* Participant is on a weight loss program that is not in the maintenance phase or has been treated with a weight loss medication within 8 weeks of screening
* Participant is on or may require treatment with drugs that affect the immune system or with corticosteroids
* Participant has a history of heart failure or coronary artery disease
* Participant has a history of uncontrolled high blood pressure
* Participant is Human Immunodeficiency (HIV), hepatitis B or hepatitis C positive
* Participant has a history of Type 1 diabetes
* Participant has a history of hypoglycemia unawareness documented by a blood glucose concentration \< 55 mg/dL (3.1 mol/L) without symptoms of hypoglycemia.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
60 Years
Study:
NCT00902161
Study Brief:
Protocol Section:
NCT00902161