Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:14 PM
Ignite Modification Date:
2025-12-24 @ 4:14 PM
NCT ID:
NCT07165366
Eligibility Criteria:
Inclusion criteria:
* Have the four premolars in different quadrants that their orthodontist recommends be extracted.
* The premolars to be extracted should have prominent facial surfaces.
* Willing to have the four premolars slightly flattened and smoothed.
* Willing to have all four premolars extracted for orthodontic reasons.
* Between 12 and 35 years of age.
* Willing to attend four appointments.
* Willing to wear a custom-made whitening tray during the evening when they sleep.
* Willing to have their premolars bleached with In-Office and At-Home bleaching agents and one of their teeth that will be extracted treated with phosphoric acid.
* Willing to sign a consent form (parents must co-sign if they are under 18).
* Willing to discontinue active orthodontic treatment during whitening treatment.
* Willing to brush at least twice a day with fluoridated toothpaste provided during the study.
Exclusion criteria:
* Restorations or visible cavities in any tooth to be extracted.
* The presence of visible intraoral structural defects or pathology.
* Use of over-the-counter or professionally prescribed whitening agents in the past six months.
* Teeth with tetracycline staining.
* History of any medical illness that may interfere with the study or require special considerations.
* Pregnant or lactating women.
* Not willing to do the blood tests (biometrics hematic, prothrombin, and thromboplastin) prior to extractions (a legal requirement of the Oral Surgery Department of the UIC).
Healthy Volunteers:
True
Sex:
ALL
Minimum Age:
12 Years
Maximum Age:
35 Years
Study:
NCT07165366
Study Brief:
Protocol Section:
NCT07165366