Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:07 PM
Ignite Modification Date:
2025-12-24 @ 4:07 PM
NCT ID:
NCT05303766
Eligibility Criteria:
* Inclusion Criteria:
1. patients diagnosed with KOA based on the American College of Rheumatology criteria
2. age 18-70 years
3. grade 2 or 3 KOA based on the Kellgren-Lawrence classification
4. patients who did not respond to conservative treatment (physiotherapy, oral NSAIDs, and/or intraarticular injections of hyaluronic acid and corticosteroid) for 3 months
5. duration of knee pain ≥ 3 months
6. numeric rating scale (NRS) ≥ 5 points within 24 h prior to admission.
* Exclusion Criteria:
1. grade 1 or 4 KOA based on the Kellgren-Lawrence classification
2. severe liver, kidney, cardiovascular, and respiratory disease
3. abnormal blood coagulation
4. skin infections in the puncture region
5. patients who previously underwent knee arthroscopy, TKA, RFTGN, or IAPRF
6. mental disorders or inability to complete the follow-up observational form
7. patients with bilateral knee pain.
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Maximum Age:
70 Years
Study:
NCT05303766
Study Brief:
Protocol Section:
NCT05303766