Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 4:01 PM
Ignite Modification Date:
2025-12-24 @ 4:01 PM
NCT ID:
NCT05605366
Eligibility Criteria:
Inclusion Criteria:
Adults (age ≥ 18 years old) with SCD (HbSS and HbS-β0thalassemia genotypes only) who are followed at the University of Cincinnati Medical Center's SCD clinic are eligible to participate. As hydroxyurea is the standard-of-care in SCD, individuals on hydroxyurea will be included
Exclusion Criteria:
1. adults with other SCD genotypes (HbSC or HbS- β+thalassemia),
2. individuals with a history of overt stroke or other known neurological disorder,
3. premature birth before 30 weeks gestation,
4. monthly therapy with chronic blood transfusions,
5. coexisting autoimmune condition due to an elevated risk for autoimmune-related complications with tetracyclines,
6. tetracycline allergy.
7. Women who are pregnant or breast-feeding
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT05605366
Study Brief:
Protocol Section:
NCT05605366