Eligibility Module
The Eligibility Module contains detailed information about who can participate in the clinical trial. This includes eligibility criteria, age restrictions, gender requirements, healthy volunteer status, and study population descriptions, helping researchers understand who is eligible to participate in the study.
Eligibility Module path is as follows:
Study -> Protocol Section -> Eligibility Module
Eligibility Module
Ignite Creation Date:
2025-12-24 @ 3:56 PM
Ignite Modification Date:
2025-12-24 @ 3:56 PM
NCT ID:
NCT06134492
Eligibility Criteria:
Inclusion Criteria:
1. ≥ 18 years
2. need for invasive or non-invasive respiratory support
3. PCR HSV-1 detection in BAL (≥ 10\^3 copies/ml)
4. Pneumonia (community or healthcare acquired, incl. ventilator-associated pneumonia)
5. declaration of consent by the patient or legal representative
Exclusion Criteria:
1. History of hypersensitivity to acyclovir or valacyclovir or other components of the investigational product.
2. Pregnancy/Lactation
3. Simultaneous participation in another interventional clinical trial
4. Decision to withhold life-sustaining therapies
5. Use of a virostatic agent (i.v. or p. os) with activity against herpes simplex (acyclovir, valacyclovir, famciclovir/penciclovir, brivudine, cidofovir, foscarnet) for therapeutic or prophylactic reasons at the time of randomization.
6. Solid organ transplantation, stem cell transplantation
7. Neutropenia (absolute neutrophil count \<1500/μl (\<1.5 × 109 /l)
8. Previous study participation in HerpMV
Healthy Volunteers:
False
Sex:
ALL
Minimum Age:
18 Years
Study:
NCT06134492
Study Brief:
Protocol Section:
NCT06134492